PYOHEX SHAMPOO

INDICATIONS
For primary or secondary Pyoderma caused by bacteria
As an adjunct to treatment for demodectic mange and other deep pyodermas
As a preventative for recurrent pyodermas
German Shephard Furunculosi
Does not irritate or dry like a Chlorhexidine scrub

SIZES
250mL, 500mL and 1L
REGISTERED FOR USE IN
Dogs and puppies of an age

ACTIVES
3% Chlorhexidine Gluconate
A proven antibacterial with activity against gram positive bacteria ie. Staphylococcus intermedius and gram negative bacteria
Non-toxic, non-irritating, with a 4 day residual activity

ACTIONS
The Chlorhexidine in PYOHEX works by binding to hair and penetrating the follicle via a wicking action down the hair shaft, to eliminate bacteria in situ. Chlorhexidine kills bacteria by disrupting the cell membrane and precipitating the cell contents.
PYOHEX binds strongly to the skin and hair, resulting in a 4 day residual action. As Chlorhexidine is poorly absorbed through the skin, PYOHEX is completely safe.
PYOHEX contains an advanced surfactant base that removes abnormal lipids that occur due to bacterial lipases. PYOHEX does not dry or strip the coat of essential lipids needed to prevent transepidermal water loss, a process that promotes infection.
PYOHEX is pH neutral, specifically designed for canine skin.

DIRECTIONS FOR USE
First wet the coat, then sponge PYOHEX onto the animal's coat and allow to stand for 10 minutes then rinse thoroughly. This is the minimum contact time to ensure antimicrobial activity. Bath twice weekly until symptoms abate and then weekly or as directed by your veterinarian.

EFFICACY
In vivo studies have revealed that a 3% Chlorhexidine solution is the optimum concentration for use as an antibacterial on skin.
Independent studies have shown that Chlorhexidine is the most efficacious antibacterial, especially against Staphylococcus intermedius, when compared to other commonly used antibacterials such as Ethyl Lactate and Benzoyl
Peroxide
In addition to it's superior antimicrobial activity, PYOHEX is the treatment of choice above standard Benzoyl Peroxide and Ethyl Lactate shampoos because:

- The Chlorhexidine in PYOHEX does not irritate the skin or hair follicle, or cause allergic reactions, nor is it a carcinogen, in contrast to Benzoyl Peroxide
- PYOHEX does not need to undergo activation in the sebaceous gland to work, like Ethyl Lactateinfection.
- Chlorhexidine does not break down, unlike Benzoyl Peroxide, which is rapidly degraded to Benzoic acid and excreted by the kidneys. The Chlorhexidine in PYOHEX is still bound to skin and hair, and still bactericidal the next day where as Benzoyl Peroxide is degraded.